Clinical Sarcoma Research

1. Extraskeletal myxoid chondrosarcoma with massive pulmonary metastases

   Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant mesenchymal neoplasm of uncertain differentiation characterized by rearrangements of the NR4A3 gene. EMC often affects adults around the age of 50...

2. A phase II study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcomas

   Relapsed and refractory sarcomas continue to have poor survival rates. The cancer stem cell (CSC) theory provides a tractable explanation for the observation that recurrences occur despite dramatic responses t...

3. Descending thoracic aortic aneurysm revealing metastasis of a soft tissue fibrosarcoma: a case report and review of the literature

   Review of the first documented case of aortic wall metastasis from a limb sarcoma.

4. Preoperative radiotherapy of soft-tissue sarcomas: surgical and radiologic parameters associated with local control and survival

   Preoperative radiotherapy is often used to facilitate excision of soft-tissue sarcomas. We aimed define factors that affect local tumour control and patient survival.

5. Periostin expression in neoplastic and non-neoplastic diseases of bone and joint

   Periostin is a matricellular protein that is expressed in bone and joint tissues. To determine the expression of periostin in primary bone tumours and to assess whether it plays a role in tumour progression, w...